Make no mistake. The answer is a big YES. Sterility methods affect not only the integrity of actives, but the safety and efficacy. Even bottles that contain micro-delivery or transepidermal delivery need to be sterilized through a safe method. For example, gamma sterilization is harmful to product's integrity. High heat destroys green tea's efficacy as another example. Micro filtration ensures integrity of functional actives' properties such as ph, efficacy, molecular weight and molecular structure. Many active ingredients most especially proteins, peptides, gallates, vitamin A/C/E, Glutathione, phenolic extracts such as grape seed/resveratrol and gallate/catechin actives are destroyed by the intensity of moist heat and gamma radiation. Our products preserve its functional actives and proudly offer healthy aesthetic treatments through micro filtration method.